Staphylococcal scalded skin syndrome https://en.wikipedia.org/wiki/Staphylococcal_scalded_skin_syndrome
https://en.wikipedia.org/wiki/Staphylococcal_scalded_skin_syndrome
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References Staphylococcal Scalded Skin Syndrome 28846262
 Staphylococcal Scalded Skin Syndrome 28846262 NIH
Staphylococcal Scalded Skin Syndrome هڪ حالت آهي جيڪا چمڙي جي زهر جي ڪري پيدا ٿئي ٿي، خاص قسم جي Staphylococcus بيڪٽيريا طرفان. هي عام طور تي ڇهن مهينن کان مٿي ٻارن ۾ غير معمولي آهي، پر بالغن ۾ به ٿي سگهي ٿو جيڪي ڪمزور مدافعتي نظام يا گردن جي سنگين مسئلن سان متاثر آهن. مکيه خصوصيت وسيع چمڙي جي ڇڪڻ کان پوءِ سوزش آهي. شدت جي حد ڪجهه ڦڦڙن جي نقصان کان وٺي چمڙي جي وڏن نقصانن تائين ٿي سگهي ٿي، جيڪا جسم جي گرمي پد ۾ سخت گهٽتائي ۽ بلڊ پريشر ۾ عدم استحڪام جو سبب بڻجي سگهي ٿي.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
 Staphylococcal Scalded Skin Syndrome and Bullous Impetigo 34833375
 Staphylococcal Scalded Skin Syndrome and Bullous Impetigo 34833375 NIH
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
 Staphylococcal Scalded Skin Syndrome in a Ten-Month-Old Male - Case reports 35989790
 Staphylococcal Scalded Skin Syndrome in a Ten-Month-Old Male - Case reports 35989790 NIH
هڪ 10 مهينن جو ڇوڪرو اندر آيو جنهن ۾ نڪ وهندي هئي ۽ سٺو نه کائي رهيو هو. ڊاڪٽرن جو چوڻ هو ته اهو اپر ريسپيريٽري انفيڪشن هو. ٻن ڏينهن کان پوءِ، هو واپس آيو ڇاڪاڻ ته هو بهتر نه ٿي رهيو هو ۽ هن کي نوان مسئلا هئا جهڙوڪ سوجن منهن ۽ وات جي چوڌاري خارش. ايندڙ ٻن ڏينهن ۾، ڇوڪرو خراب ٿي ويو. هن جا هٿ ۽ ٽنگون سُور ٿي ويون ۽ هن جي چمڙي نڪرڻ لڳي. واپس اسپتال ۾، ڊاڪٽرن هن جي منهن تي هڪ ڳاڙهي داڻا ڏٺا ۽ هن جي چمڙي جي پاڙن ۾، جيڪو جڏهن ڇڪيو ويو ته ڦوڪيو. انهن هن کي staphylococcal scalded skin syndrome (SSSS) جي تشخيص ڪئي ۽ هن کي هڪ رڳ ذريعي اينٽي بايوٽڪ تي شروع ڪيو.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
 Staphylococcal scalded skin syndrome - Case reports 23761500
 Staphylococcal scalded skin syndrome - Case reports 23761500 NIH
هڪ 2 ورهين جي ڇوڪريءَ جي سڄي جسم تي ريش ظاهر ٿيا جيڪي 48 ڪلاڪن کان مٿي موجود هئا، هڪ ڏينهن اڳ هن جي منھن ۾ ڪيڙا کائڻ بعد. معائني دوران، هن کي وسيع ريش مليو جيڪو ننڍن ٿنڊن مان ٺهيل هو، جيڪي پاڻ ۾ ضم ٿي ويا هئا، ۽ جڏهن دٻايو ويو ته هن جي چمڙي تي نڪولسڪي(Nikolsky) جي نشان ظاهر ٿيا. مغز جي جھلي کي متاثر ڪندڙ ريش جا ڪو به نشان نه هئا. رت جي ٽيسٽن ۾ انفڪشن جا نشان نه ملن.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
 
سنڊوم ايپيڊرموليٽڪ ايڪسوٽڪسين (exfoliatin) A ۽ B جي ڪري پيدا ٿئي ٿو، جيڪي S. aureus پاران پيدا ڪيا ويندا آهن. ٻارن ۾ Staphylococcal scalded skin syndrome جي اڳڪٿي بهتر آهي؛ علاج جي 10 ڏينهن اندر مڪمل بحالي حاصل ٿيندي آهي، ۽ داغ باقي نه رهندا. تنهن هوندي به، Staphylococcal scalded skin syndrome کي احتياط سان toxic epidermal necrolysis کان الڳ ڪرڻ گهرجي، جيڪو خراب پروگنوسس جو سبب بڻجي ٿو.
○ تشخيص ۽ علاج
eczema جي زخمن جي غلط تشخيص، جهڙوڪ atopic dermatitis، ۽ اسٽيرائڊ عطر جو استعمال زخمن کي وڌائي ٿو. اينٽي بايوٽڪ عطر لاڳو ڪرڻ دوران جلد کان جلد طبي مدد طلب ڪريو.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)