Staphylococcal scalded skin syndrome
☆ 2022 ۾ جرمني مان Stiftung Warentest نتيجن، ModelDerm سان صارفين جي اطمينان صرف ادا ڪيل ٽيلي ميڊيسن مشوري جي ڀيٽ ۾ ٿورو گهٽ هئي.
References
Staphylococcal Scalded Skin Syndrome هڪ حالت آهي جتي چمڙي جي زهر جي ڪري پيدا ٿئي ٿي، خاص قسم جي Staphylococcus بيڪٽيريا طرفان پيدا ڪيل. ڇهن کان مٿي ٻارن ۾ اهو غير معمولي آهي. اهو بالغن ۾ پڻ ٿي سگهي ٿو جيڪي ڪمزور مدافعتي نظام يا گردڪ جي سنگين مسئلن سان. مکيه خصوصيت آهي وسيع چمڙي جي ڇڪڻ کانپوءِ سوزش. شدت جي حد ڪجھ ڦڦڙن کان وٺي چمڙي جي وڏي نقصان تائين، جيڪا جسم جي گرمي پد ۾ سخت گهٽتائي ۽ بلڊ پريشر ۾ عدم استحڪام جو سبب بڻجي سگهي ٿي.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
هڪ 10 مهينن جو ڇوڪرو اندر آيو جنهن ۾ نڪ وهندي هئي ۽ سٺو نه کائي رهيو هو. ڊاڪٽرن جو چوڻ هو ته اهو اپر ريسپيريٽري انفيڪشن هو. ٻن ڏينهن کان پوءِ، هو واپس آيو ڇاڪاڻ ته هو بهتر نه ٿي رهيو هو ۽ هن کي نوان مسئلا هئا جهڙوڪ سوجن منهن ۽ وات جي چوڌاري خارش. ايندڙ ٻن ڏينهن ۾، ڇوڪرو خراب ٿي ويو. هن جا هٿ ۽ ٽنگون سُور ٿي ويون ۽ هن جي چمڙي نڪرڻ لڳي. واپس اسپتال ۾، ڊاڪٽرن هن جي منهن تي هڪ ڳاڙهي داڻا ڏٺا ۽ هن جي چمڙي جي پاڙن ۾، جيڪو جڏهن ڇڪيو ويو ته ڦوڪيو. انهن هن کي staphylococcal scalded skin syndrome (SSSS) جي تشخيص ڪئي ۽ هن کي هڪ رڳ ذريعي اينٽي بايوٽڪ تي شروع ڪيو.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
هڪ 2 ورهين جي ڇوڪريءَ جي سڄي جسم تي ريش نظر آيا جيڪي 48 ڪلاڪن کان مٿي ٿي چڪا هئا، هڪ ڏينهن اڳ هن جي منهن تي ڪيڙا کائڻ بعد. امتحان دوران، هن کي هڪ وسيع ريش هئي، جيڪا هڪ ننڍڙي ٿڌن مان ٺهيل هئي، جيڪي پاڻ ۾ ضم ٿي ويا هئا، ۽ جڏهن هن کي هلڪو ڪيو ويو ته هن جي چمڙي تي نڪولسڪي جي نشانين جا نشان ظاهر ٿيا. هن جي مغز جھلي کي متاثر ڪندڙ ريش جا ڪي به نشان نه هئا. هن جي رت تي ٽيسٽن ۾ انفيڪشن جا نشان ظاهر نه ٿيا.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
سنڊوم ايپيڊرموليٽڪ ايڪسوٽڪسين (exfoliatin) A ۽ B جي ڪري پيدا ٿئي ٿو، جيڪي S. aureus پاران جاري ڪيا ويا آهن. ٻارن ۾ staphylococcal scalded skin syndrome جي اڳڪٿي شاندار آهي، علاج جي 10 ڏينهن اندر مڪمل حل سان، ۽ بغير ڪنهن داغ جي. تنهن هوندي به، staphylococcal scalded skin syndrome کي احتياط سان toxic epidermal necrolysis کان الڳ ڪرڻ گهرجي، جيڪو خراب پروگنوسس ڪري ٿو.
○ تشخيص ۽ علاج
eczema جي زخمن جي غلط تشخيص جيئن ته atopic dermatitis، ۽ اسٽيرائڊ عطر جو استعمال زخمن کي وڌائي ٿو. اينٽي بايوٽڪ عطر لاڳو ڪرڻ دوران مهرباني ڪري جلد کان جلد طبي ڌيان طلب ڪريو.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)